The Lumito SCIZYS system is an open platform for immunohistochemistry (IHC). The SCIZYS UCNPs can be attached to any biotinylated molecule and the system is agnostic to tissue type, enabling a wide range of uses. We are co-developing application areas together with our customers and partners. Areas with significant interest and potential include:

• Optimising cut points for patient stratification for the next generation of ADCs

• Quantitative displacement experiments in development of ADCs
• Measuring subtle changes in pre-clinical models for degenerative diseases where traditional IHC images appear saturated

• Tissue Cross Reactivity studies
• Replacing visual categorization with quantitative analysis during drug development

• Algorithmic quantification of specific biomarkers, using morphology and biomarker expression from different channels in the same sample
• A very sensitive and stable label complementing multiplexed immunofluorescence studies
• Virtual annotations in development of immunohistochemistry AI applications