Scientific articles

Our technology is currently being utilised to highlight our system’s versatility and potential to become the next generation’s immunohistochemistry (IHC) detection system in tissue diagnostics. Our involvement in these studies aims to showcase the range of different applications our technology can be used for. Each pilot study contributes to improving our understanding of the capability and flexibility of our technology, while also exploring new opportunities and applications in the field.

Scientific Articles

White Paper: A Novel Tool for Immunohistochemistry: SCIZYS by Lumito

June 2024. Lumito AB.

High contrast breast cancer biomarker semi-quantification and immunohistochemistry imaging using upconverting nanoparticles

January 2024. Tyndall National Institute i Cork, Irland.

Upconversion Nanoparticles as labels for histopathological tissue evaluation

September 2023. Lumito AB.

Utility of Upconversion Nanoparticles (UCNP) Based Immunohistochemistry in Diagnostic Renal Biopsies – A Proof of Concept Study

July 2023. University Hospital Coventry and Warwickshire (UHCW) NHS Trust, Coventry, UK.

Extracellular Galectin 4 Drives Immune Evasion and Promotes T-cell Apoptosis in Pancreatic Cancer

January 2023. Umeå University.

Completed Pilot Studies

International pilot study in collaboration with a research group at University Hospitals Coventry and Warwickshire in the United Kingdom

Purpose:

The study focused on detecting immunocomplex and complement deposition in renal biopsies using Lumito’s technology.

Results:

The results will be presented in June at Liverpool Congress Pathology 2023 through a poster presentation.

Collaboration with a research group at Umeå University in Sweden

Purpose:

The study explored the capacity of Lumito’s technology when quantifying signals compared to traditional DAB staining.

Results:

The study proved that Lumito’s technology offers more precise measurement results compared to traditional DAB staining, which saturates quickly and decreases the possibility of correct quantification. The research group in Umeå wrote an article about the study published in Cancer Immunology Research. See a presentation of the results here.

Testing SCIZYS is simple!

We’ve made it easy for you to try SCIZYS. Purchase our kit to stain your tissue samples, and we’ll scan them for you. You’ll receive high-resolution digital images ready for analysis in your preferred software.

Please feel free to reach out if you have any questions or want to explore how SCIZYS can support your research needs.